The All of Us Researcher Workbench is a cloud-based platform where registered researchers can access Registered and Controlled Tier data. Its powerful tools support data analysis and collaboration. It also offers two useful hubs:

  • The Workbench User Support Hub that provides integrated help and educational resources
  • The All of Us Research Hub that matches a broad research community with a diverse set of research participants. Its goal is to advance precision medicine research and fuel new insights into human health. This hub houses one of the largest, most diverse, and most broadly accessible datasets ever assembled.

All of Us Data and Tools

Data Browser

The Data Browser includes Public Tier aggregate data from physical measurements, surveys, and electronic health records, including concepts.

Data Snapshot

The Data Snapshots include data visualizations showing the participant cohort size and attributes, including how many participants are from groups underrepresented in biomedical research.

Data Access Tiers

There are three tiers available:

  1. Public Tier: Contains only aggregate data with identifiers removed
  2. Registered Tier: Contains individual-level data, available only to approved researchers on the Researcher Workbench (currently includes data from electronic health records [EHRs], wearables, surveys, and physical measurements)
  3. Controlled Tier: Contains genomic data in the form of short-read whole genome sequences (WGS), long-read WGS, structural variants, and genotyping arrays, previously suppressed demographic data fields from EHRs and surveys, and unshifted dates of events.

Data Methods

The data curation process uses Observational Medical Outcomes Partnership (OMOP) to standardize data to ensure high-quality data for research.

Data Sources

Participant data available for research include information from electronic health records (EHRs), physical measurements, survey responses, wearables data, and genomic data from biosamples. We will add new participant data sources as the program grows.

Survey Explorer

This tool provides source information for the surveys that All of Us asks participants to complete, including each individual question. Aggregate responses to the surveys are available in the Data Browser.

How to Use All of Us

Accessing the Researcher Workbench data is easy and takes only a few steps. If you are interested in applying for Researcher Workbench access, visit the All of Us Register page for information on the steps you will need to complete.

Visit the About the Research Hub page for more information about how the platform operates.

All Authorized Data Users are required to treat all Participant Data and any other non-public information pertaining to participants obtained from the Research Hub as confidential and only use such data and other information for the purposes of an active biomedical or health research study that is being conducted under the auspices of the User Institution. Researchers should always check with their local institutional review board to ensure compliance with local requirements for conduct of research.

Within the Cloud-based environment of the Researcher Workbench, registered researchers use R, Python, or SAS to link and analyze a variety of data types — surveys, physical measurements, electronic health records (EHRs), wearables, genomics — to conduct a wide range of studies.

The All of Us Research Program employs Observational Medical Outcomes Partnership (OMOP) Common Data Model Version 5 infrastructure to ensure feasibility and standardization across all program data types (physical measurements, electronic health records, and participant provided information). Data coming from disparate sources are standardized and stored in a set of formally described tables with defined relationships. This allows data to be accessed and connected in many different ways by researchers.

Visit the OHDSI website to learn more about the OHDSI OMOP CDM initiative.

As a condition of your data access, you must inform the program of any upcoming publications resulting from access to All of Us Research Program data at least two weeks before the date of publication or presentation. This includes peer-reviewed manuscripts, conference abstracts, and/or presentations.

You can inform the program about your upcoming publications by contacting User Support in your Researcher Workbench account. Note that your manuscript will not go through program review. The information will only be used to help the program prepare for any media coverage or communication surrounding the upcoming publication. Embargoes will be honored. Additionally, users must submit an electronic version of a final, peer-reviewed manuscript to PubMed Central immediately upon acceptance for publication, to be made publicly available immediately without any embargo period once published.

Contact

Email jill.zimbelman@unlv.edu if you have any questions about All of Us.