An eligible principal investigator must be the official researcher of record on all UNLV human subjects protocols. Please review the PI Eligibility Policy to determine who may serve in this role. Students may not serve in the role of PI on a research project; however, they may submit protocols as student investigators working under a faculty member who serves as the PI on the study.
Researchers may submit a study proposal through the Cayuse online submission system. Basic steps for registering a new user account are available on our website. All proposal packages must be certified by the PI listed on the protocol in order to be accepted for review. For additional assistance on submitting a proposal package, contact the Office of Research Integrity – Human Subjects at 702-895-2794 or IRB@unlv.edu.
What to Submit for IRB Review
Information about the basic materials that make up an IRB protocol submission can be found on our Getting Started page.
Please be advised that all current versions of forms are available for download from our website.
Update a Protocol
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Modification Request
Any change to an existing approved protocol must be reviewed and approved by the IRB prior to implementing the change, except when the change is necessary to eliminate apparent immediate hazards to subjects. Modification requests must be submitted through the Cayuse online submission system.
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Continuing Review Request
It is the PI’s responsibility to submit an application for continuing review insufficient time to permit the IRB to review the application prior to its expiration date. Continuing review information should be submitted as a Renewal through the Cayuse online submission system.
Note: No human subjects activity may take place after the expiration date of the protocol except to prevent potential harm to participants.