Dr. Jeffrey Cummings (Integrated Health Sciences), research professor in the Department of Brain Health and director of the Chambers-Grundy Center for Transformative Neuroscience, will serve as a keynote speaker during the Clinical Trials in Alzheimer's Disease conference in Boston, Massachusetts, on Oct. 24. Cummings has also been a co-…

Research professor and director Jeffrey Cummings, (Brain Health, Chambers-Grundy Center for Transformative Neuroscience) and director Jamie Schwartz (Industry and Business Engagement, Economic Development) were awarded a $1.5 million INNOVATOR grant from the National Institute of Aging (NIA). This five-year grant will help the…

Dr. Jeff Cummings (Brain Health) published "Trial of Pimavanserin in Dementia-Related Psychosis" in the New England Journal of Medicine.       

Jeffrey Cummings (Brain Health) co-authored a paper published in Nature on developing the ATX(N) classification, a system for recognizing biomarkers in blood that indicate the presence in the brain of plaques and tangles characteristic of Alzheimer’s disease.  ATX(N) advances allow researchers to diagnose Alzheimer’s disease without…

Dr. Jeffrey Cummings (Brain Health) recently published an article outlining a novel method for determining whether Alzheimer’s drug treatments in clinical trials are ready to move on to the next phase. The paper, “Translational Scoring of Candidate Treatments for Alzheimer’s Disease: A Systematic Approach,” was published in The Journal of…

Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Role of Clinical Trials in Preclinical Alzheimer’s Disease Drug Development Programs," in the Journal of Prevention of Alzheimer’s Disease. The somewhat provocative findings note that despite the trend toward prevention trials becoming more likely (in part because trials…

Dr. Jeffery Cummings (Brain Health) and other members of a joint European Union/United States Task Force recently published, “Non-Amyloid Approaches to Disease Modification for Alzheimer’s Disease” in the Journal of Prevention of Alzheimer’s Disease. In recognition of the complexity of the disease, the task force acknowledges it may…

Dr. Jeffrey Cummings (Brain Health), recently published an article, “An Actigraphy-Based Validation Study of the Sleep Disorder Inventory (SDI) in the Nursing Home" in Frontiers in Psychiatry. It studied the use of the SDI to identify disrupted sleep in dementia patients in nursing homes, which was proven to be useful when done properly…

Dr. Jeffery Cummings (Brain Health) and other members of a joint European Union/United States Task Force recently published, “The Future of Anti-Amyloid Trials,” in the Journal of Prevention and Alzheimer’s Disease. The authors analyze the impact of multiple clinical trials that recently ended for a variety of reasons on the Alzheimer's disease…

Dr. Jeffrey Cummings (Brain Health) recently published an article, “The Neuropsychiatric Inventory (NPI): Development and Applications,” in the Journal of Geriatric Psychiatry and Neurology. The article reviews the development of the NPI assessment tool since Dr. Cummings first introduced it 25 years ago and which has been used in…

Dr. Jeffrey Cummings (Brain Health) co-authored “Anti-Tau Trials for Alzheimer’s Disease: A Report from the EU/US/CTAD Task Force,” which explored incorporating tau biomarkers in clinical trials to provide additional knowledge about the potential for treating Alzheimer’s Disease by targeting tau. This represents a new direction in Alzheimer’s…