Dr. Nabil Noureddin (Medicine) recently published his article “Progression of Nonalcoholic Fatty Liver Disease-Associated Fibrosis in a Large Cohort of Patients with Type 2 Diabetes” in the Digestive Diseases and Sciences Journal. He is the first author on this original research that aimed to provide large-scale data on progression and regression of fibrosis in diabetics with Nonalcoholic fatty liver disease (NAFLD), which is the most common cause of chronic liver disease and cirrhosis.
The project studied a cohort of patients that included 50,695 diabetics with NAFLD and followed them for a long period (median follow-up of 84.4 months). Noureddin and his co-authors found that 25 percent of patients transitioned from no advanced fibrosis to advanced fibrosis (progression). Factors associated with transition to advanced fibrosis were female sex, older age at first evaluation, African-American race, obesity, chronic kidney disease, or coronary artery disease. The authors concluded that these findings indicate the need for early detection and staging of NAFLD in diabetics.
He is the chief resident in the department of internal medicine.