Jun Kang (Chemistry and Biochemistry) has been awarded a patent granted by the U.S. Patent and Trademark Office for the invention “Methods and Compositions for Substituted Alpha-Aminophosphonate Analogues.” This synthetic method would enable a rapid synthesis of bioactive phosphorus-containing compounds and pharmaceuticals under toxic metal-free conditions.
This invention describes efficient, mild, toxic metal-free synthetic methods of aminophosphonates, which have attracted great attention among scientists including chemists, biochemists, and biologists due to their broad spectrum of biomedical applications. They are well known as pharmaceutically and biologically important compounds.