Jennifer R. Pharr (Public Health) & Kavita Batra (Medicine) were recently appointed as guest editors for a special issue titled "The Impact of Exercise on the Mental Health and Quality of Life of People" in the journal Healthcare. This special issue aims to publish innovative studies (original investigations and review articles) that explore the relationship between physical activity, exercise, or sports participation and mindfulness interventions on the mental health and quality of life of specific populations. Studies many include the impact of the frequency, duration, or intensity of physical activity on outcomes such as depression, psychological distress, quality of life, or well-being.