Farhad Shokoohi (Mathematical Sciences) and his collaborators have published a paper in Biomolecules titled, "Identifying Differential Methylation in Cancer Epigenetics via a Bayesian Functional Regression Model," as part of the Special Issue on DNA Methylation in Human Diseases. The paper introduces an efficient method for identifying differentially methylated genes and DNA regions associated with diseases such as cancer. Additionally, the authors have developed a statistical package called DMCFB, now available on Bioconductor.org. Through their real data analysis, they discovered differential methylation at several binding sites of the fused gene involved in acute promyelocytic leukemia.
